Actually, given a half-life of 140 days, after 280 days approximately 3/4 (75%) will have decayed, leaving 25% still active and emitting radiation. After 420 days (i.e., 3 half-lives), about 7/8 (87.5%) will have decayed, leaving 12.5% active. (Radioactive decay is exponential; after each half-life period, about half of the remainder decays.)
Anyway, so if we assume that someone slipped some Po-210 into his food about 30 days before he died, then 30/140 means that approximately 1/5 (.2) of a half-life had expired. So using this formula:
100% / 2^(.2) = percent of polonium left after 30 days = about 87%
Meaning that about 13% of the Po-210 would have decayed in that time. Given a sufficiently large starting mass of the polonium, 13% translates to a sh*tload of alpha particles irradiating you from the inside out.
So the real question to ask is, how much Po-210 in grams would they have had to dose Litvinenko with in order for him to die of acute radiation poisoning in just 30 days (rather than dying of leukemia 5 years later, for example)?
And that's actually a question that no one knows the exact answer to -- basically because there are so few known human cases. (Besides Litvinenko's alleged poisoning, Marie Curie's daughter Irène died from accidentally inhaling polonium -- but from leukemia, a full 10 years after the laboratory accident.)
So we can only make crude estimates based on tests done with rats, and then scale up to the body weight of a typical adult man. Also the quantity needed would depend in part on the chemical form of the polonium that was given -- for example, an oxide of polonium might be absorbed by the body differently than a polonium chloride salt. But the amount, for sure, would be a tiny fraction of a milligram; perhaps a few dozen micrograms.
But again, that "10-50 micrograms" estimate is assuming that you're trying to cause extremely acute radiation poisoning that will kill someone within the course of several weeks -- you'd need much less than a microgram of Po-210 if you simply wanted to increase someone's odds of developing leukemia.



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