Quote Originally Posted by chaika
what is the "register". Register is the level of language, for example, slang, standard colloquial, formal.

So is it equivalent to
Without a doubt. / No doubt about it.
or
You betcha! (You bet!)

In an article about literacy, would I write
В современной России имеем дело с одним из самых образованных народов мира, ничего не скажешь.
I'd say that 'ничего не скажешь' is equivalent to 'without a doubt' in your example. You know that 'you betcha' is too informal for a sentence like this.