1. If "course" means "type" or "method", then you can substitute "course of chemotherapy" with "chemotherapy treatment".
The doctor's chose antimetabolite chemotherapy as the perferred course of chemotherapy for Kylie's breast cancer.
Kylie took the course of chemotherapy the doctor's prescribed.
Kylie took the type of chemotherapy treatment that the doctor's recommended.
You can substitue "course of chemotherapy" with "chemotherapy treatment" and there is NO change in meaning.
Kylie took the chemotherapy treatment the doctor's prescribed.
or to be more specific
Kylie took the antimetabolite chemotherapy the doctor's prescribed.
2. If "course" means a "decision" or "choice" over other methods of treatment, then you CANNOT substitute "course of chemotherapy" with "chemotherapy treatment".
The doctor's chose chemotherapy over surgery as the perferred course of treatement for Kylie's breast cancer.
Kylie took the course of chemotherapy the doctor's prescribed.
i.e. Kylie took the course the doctor's prescribed which was chemotherapy.
You cannot replace "course of chemotherapy" with "chemotherapy treatment" because the meaning changes.
TATY's sentence sounds natural. In this sentence, the word "course" has the meaning "type" or "method".Originally Posted by TATY
You can replace "course of chemotherapy" with "chemotherapy treatment" and the resulting sentence sounds natural and there is no change in meaning.
Are you are saying "course" means "a specific, discrete cycle"?Originally Posted by scotcher
I could not find such a definition for "course".
http://www.google.com/search?hl=en&lr=& ... ine:course