Вы звонили домой? Did you try to phone home?
Вы позвонили домой? Did you phone home/Have you phoned home?
I doubt the difference can be expressed via English tenses solely, rather than with auxiliary verbs like "try".
I think the former variant is used more often, because such a question usually implies that it is unknown whether one called home at all.
The latter variant is more definite (perfective), and it's more about asking a specific question about a specific call you wanted to make.
Note that aspects have slightly different meanings in interrogative sentences, as opposed to declarative sentences.