I’m wondering if the word "to affect" always means "to influence in a negative way"? I’ve found its three meanings in the Free Dictionary and they all seem to approve my supposition. Is it true?

1. To have an influence on or effect a change in: Inflation affects the buying power of the dollar.
2. To act on the emotions of; touch or move.
3. To attack or infect, as a disease: Rheumatic fever can affect the heart.