Yes, actually, I need to translate the part "не вызывает привыкание". (Этот препарат не вызывает привыкание)

I faced with the problem of how to express it in English. When any preparation eventually loose its effect we call it "привыкание" (it does not matter what I'm talking about - medicine or poison). Situation, when the organism gradually adapts to the preparation and it is no longer valid.